I finally upgraded my office machine to OS X Mavericks, and as a result had to reconfigure both Apache and MySQL.
This post covers most of the relevant info for dealing with Apache: remapping your default web directory, enabling PHP. This post deals with setting index.php as a default document if a directory is requested.
One random note: Launchbar’s ClipMerge feature stopped working, and it turns out that was because Mavericks resets the Accessibility options. I had to go to System Preferences > Security & Privacy > Accessibility and allow Launchbar to control my computer.